Cisplatin allergy
WebCisplatin is an irritant. An irritant is a chemical that can cause inflammation of the vein through which it is given. If cisplatin escapes from the vein it can cause tissue damage. … Webfatal, allergic reaction on re-exposure, but alternative drugs might be poorly tolerated or much less effective compared with the preferred agent. ... cisplatin, oxaliplatin, paclitaxel, liposomal doxorubicin, doxorubicin, or rituximab received rapid desensitization to these agents. A standardized 12-step
Cisplatin allergy
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WebAug 4, 2024 · In recent years, the increased use of platinum-based drugs in clinical applications has increased the incidence rates of platinum allergy. Studies have reported the incidence rate of carboplatin allergy to be 1–44% [1,2,3], cisplatin allergy to be 5–20% [] and oxaliplatin allergy to be 10–18.9% [5, 6].Given the heavy use of platinum-based … WebMar 8, 2024 · Although many carboplatin-allergic patients tolerate cisplatin [ 54 ], there is some degree of potentially fatal cross-reactivity between carboplatin and cisplatin. …
WebThe treatment with cisplatin was generally well tolerated. No serious allergic reactions occurred. A mild allergic reaction was recorded (urticaria) in only one case, after one cycle of cisplatin, and the patient was not rechallenged because of progressive disease. No reductions of chemotherapy doses were needed. Web2 days ago · Cisplatin is used successfully in the chemotherapy of testicular cancer. However, patients who develop resistance to the cytostatic drug urgently need alternative therapy options.
WebJun 7, 2015 · Cisplatin, a first-generation platinum agent, is a non-natural compound that was serendipitously discovered during a work conducted by Rosenberg et al. ( 1 ). For its efficacy, it is recommended that treatment be discontinued after a maximum of six cycles when treating non-small cell lung cancer ( 2, 3 ). WebDec 12, 2024 · This drug may lower the ability of the bone marrow to make blood cells that the body needs. If blood cell counts get very low, this can lead to bleeding problems, infections, or anemia. Some infections have been severe and even deadly. If you have questions, talk with the doctor.
WebApr 14, 2024 · Among the extracellular vesicles, apoptotic bodies (ABs) are only formed during the apoptosis and perform a relevant role in the pathogenesis of different diseases. Recently, it has been demonstrated that ABs from human renal proximal tubular HK-2 cells, either induced by cisplatin or by UV light, can lead to further apoptotic death in …
WebJan 19, 2024 · The cytotoxic agents that are most commonly associated with infusion reactions are the taxanes, platinum drugs, pegylated liposomal doxorubicin, … how brain increase heart rateWebAllergic responses in industrial workers exposed to platinum salts have been reported since 1945 ( 10) and allergic hypersensitivity reactions to platinum chemotherapeutics are … how brain drain worksWebFeb 16, 2024 · Common side effects of cisplatin may include: hearing problems; kidney problems; numbness or tingling; nausea, vomiting; or bone marrow suppression. how many pages in an hourWebCisplatin is a chemotherapy drug used to treat testicular, ovarian, bladder, head and neck, lung and cervical cancer. It may also be used to treat other cancers. It is best to read this information with our general information about chemotherapy and the type of cancer you have. Your doctor will talk to you about this treatment and its possible ... how many pages in alice in wonderlandWebChemotherapy protocol: The TP chemotherapy regimen used was paclitaxel liposome 135 mg/m 2 d1 plus cisplatin 25 mg/m 2 d1‐3 every 3 weeks. The PF group was 5‐FU 600 mg/m 2 d1‐3 and cisplatin 25 mg/m 2 d1‐3 every 4 weeks. Chemotherapy was simultaneously supplemented with antiemetic, anti‐allergy, and other symptomatic … how brahe\u0027s work help keplerWebApr 10, 2024 · Cisplatin Nephrotoxicity - Clinical Features and Treatment. Cisplatin nephrotoxicity is one of the side effects of Cisplatin, a chemotherapeutic agent. Read this article to learn about cisplatin nephrotoxicity. Dr. Sri Ramya M 10 Apr 2024 - 4 min read. Disclaimer: No content published on this website is intended to be a substitute for ... how brain freeze worksWebPlatins can be irritants when used in skin testing; therefore, in vitro testing may offer an alternative diagnostic tool. Objective: To evaluate sensitivity and specificity of platin specific IgE (sIgE) in patients with HSRs and in controls. Methods: The control group included 17 patients exposed to platin and with no HSR. how brain interprets sound