Hif1a是什么蛋白
WebReceive email alerts when new plasmids with this gene become available. Log in to subscribe to Addgene Alerts. Description hypoxia inducible factor 1 subunit alpha. Also … Web14 de dez. de 2024 · 以上数据表明，HIF1a累积引起的Sox10表达降低对于少突胶质细胞分化中HIF介导的阻滞至关重要，在不改变sgVhl OPC中经典HIF功能的情况下恢复Sox10表达可恢复少突胶质细胞的形成。. 最后，为了评估MEK抑制在低氧人脑OPC中的作用，作者利用先前建立的从多能干细胞中 ...
Hif1a是什么蛋白
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WebFurthermore, HIF1A expression was found to be positively associated with both tumor immune infiltration and PD-L1 expression, indicating that tumors with elevated expression of HIF1A may exhibit a more active immunotherapy response. This indication was substantiated in a kidney cancer cohort receiving anti-PD-1/PD-L1 immunotherapy. http://www.biofeng.com/gene/renyuan/HIF1A.html
Web综上所述，HIF-1α、VEGF-A、MMP-9在血管源性脑水肿中具有双峰表达模式及功能双向性，在脑损伤早期促进BBB破坏和血管源性脑水肿的形成，在脑损伤后期则有利于血管生成、神经保护。. 它们在脑损伤后的双重作用导致了不同时间窗给药将导致不同的预后，因此 ... Web131 linhas · 4 de abr. de 2024 · Title: HIF1-α upregulation induces proinflammatory factors to boost host killing capacity after Aspergillus fumigatus exposure. Hypoxia-Inducible …
WebFull gene name according to HGNC. Hypoxia inducible factor 1 subunit alpha. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to … Web17 de jan. de 2024 · Taken together, this study demonstrates the key function of the hypoxia-associated transcription factor HIF-1α in driving IL-10 expression in CD1d hi CD5 + B cells, and in controlling their...
WebThe transcription factor hypoxia inducible factor-1α (HIF-1α) mediates adaptive responses to oxidative stress by nuclear translocation and regulation of gene expression. …
Web7 de jun. de 2013 · STUB1 is a critical player in the CMA-dependent degradation of HIF1A. ARPE-19 cells were transfected with STUB1-myc and incubated either in the presence or absence of 200 μM chloroquine, 20 μM MG-132 or 2% O 2 for 8 h or 300 μM CoCl 2 for 6 h. ( A) Immunoprecipitation of myc-tagged STUB1. iphone 6s verizon refurbishedWebInteracts with the ARNT; forms a heterodimer that binds core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters (PubMed:26245371). Interacts with COPS5; the interaction increases the transcriptional activity of HIF1A through increased stability (PubMed:11707426). Interacts with EP300 (via TAZ-type 1 domains); … orange and magentaWeb8 linhas · Sequence. Sequence: Please enter your sequence in the 5' to 3' direction. … iphone 6s verizon wireless priceWeb26 de fev. de 2024 · To investigate the contributions of HIF-1α in regulating glycolysis of cancer cells under hypoxia, we evaluated the dynamics of HIF-1α protein and its target … orange and marshmallow saladWeb30 de out. de 2024 · Our data indicate that FABP5 is a critical fatty-acid sensor in HCC, as it promotes HCC progression and poor prognosis by activating HIF-1α. Due to poor … orange and moreWeb25 de jun. de 2015 · Xihua Chen, Jianbing Liu, Bin He, Yunfeng Li, Shuyan Liu, Bin Wu, Shufang Wang, Shucheng Zhang, Xiangbo Xu, Jiedong Wang, Vascular endothelial growth factor (VEGF) regulation by hypoxia inducible factor-1 alpha (HIF1A) starts and peaks during endometrial breakdown, not repair, in a mouse menstrual-like model, Human … iphone 6s vs x cameraWeb3 de mar. de 2024 · Hypoxia-inducible factor 1 (HIF1) is a heterodimeric transcription factor, consisting of a constitutively expressed β-subunit (HIF1B) and a regulated α-subunit … iphone 6s vs iphone 7 camera specs